MAAFIM 6th International Conference 2026

“Integrated Clinical Protocols for Autism Spectrum Disorder: A Lifespan Perspective.”
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by impairments in social communication, restricted behaviors, and sensory processing abnormalities. Increasing evidence suggests that ASD arises from multifactorial interactions involving genetic susceptibility, environmental exposures, metabolic disturbances, and neuroimmune dysregulation. Emerging research highlights the potential role of oxidative stress, neuroinflammation, gut–brain axis dysfunction, and toxic exposures in altering early brain development and neural connectivity. Integrative clinical approaches aim to address these underlying contributors through comprehensive assessment and individualized treatment strategies. These may include evaluation of nutritional status, gastrointestinal health, toxic burden, metabolic function, and neurochemical balance. Therapeutic interventions often focus on dietary modification, detoxification support, targeted nutritional supplementation, microbiome restoration, and neurorehabilitation strategies such as neurofeedback and craniosacral therapy. Early identification and intervention remain critical for improving developmental outcomes. A holistic, systems-biology perspective may provide a broader framework for understanding ASD and guiding personalized therapeutic strategies across the lifespan.